Liquid chromatography capillary, open tubular, Immobilized

In gais chromatography (GC), open-tubular caplllaury columns cam produce much more theoretical plate numbers tham conventional packed columns. Open-tubular capillary columns have been examined am separation tools also in liquid chromatography(LC)(8-12). Coated columns, ca. 20 m X 10-30 vim l.d., produced theoretical plate numbers in excess of 100,000 but long-term stability of these columns was scxnewhat poor even if the mobile phame is saturated with the mobile phase. Accordingly chemically bonded or immobilized stationaury phatses should be preferred. 

---