Liposome microscopic investigations

Microscopic Investigations of Liposome Uptake by Dendritic Cells... 

It is now believed from studies on the natural photosynthetic systems that microenvironments for the photoinduced ET reaction play an important role in the suppression of the back ET [1-3]. As such reaction environments, molecular assembly systems such as micelles [4], liposomes [5], microemulsions [6-8] and colloids [9] have been extensively investigated. In them, the presence of microscopically heterogeneous phases and interfacial electrostatic potential is the key to the ET rate control. 

Liposomes are microscopic closed vesicles composed of a bilayered phospholipid membrane. The ability of liposomes to transport dmgs or other bioactive molecules to various tissues has been a subject of extensive investigation for some time. Among various routes of administration, oral dosing is the simplest and has obvious advantages, and a number of studies have been performed to investigate uptake and biodistribution of liposomes following oral delivery (Das eta/., 1984 Aramaki eta/., 1993). 

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