Lipopolysaccharide structure Pseudomonas

S. G. Wilkinson, L. Galbraith, and W. J. Anderton, Lipopolysaccharides from Pseudomonas maltophilia composition of the lipopolysaccharide and structure of the side-chain polysaccharide from strainN.C.I.B. 9204, Carbohydr. Res., 112 (1983) 241-252. 

Leone, S., Izzo, V., Sturiale, L., Garozzo, D., Lanzetta, R., Parrilli, M., Molinaro, A., Di Donato, A. Structure of minor oligosaccharides from the lipopolysaccharide fraction of Pseudomonas stutzeri OX1. Carbohydr Res 339 (2004b) 2657-2665. 

Kulshin, V.A., Zahringer, U., Lindner, B., Jager, K.E., Dmitriev, B.A., Rietschel, E.T. Structural characterization of the lipid A component of Pseudomonas aeruginosa wild-type and rough mutant lipopolysaccharides. Eur J Biochem 198 (1991) 697-704. 

U. Zahringer, H. Rettenmaier, H. Moll, S. N. Senchenkova, and Y. A. Knirel, Structure of a new 6-deoxy-ot-D-talan from Burkholderia (Pseudomonas) plantarii strain DSM 6535, which is different from the O-chain of the lipopolysaccharide, Carbohydr. Res., 300 (1997) 143-151. 

Y. A. Knirel, A. S. Shashkov, M. A. Soldatkina, N. A. Paramonov, and I. I. Zakharova, Antigenic polysaccharides of bacteria 32. The structure of O-specific polysaccharide chains of Pseudomonas cepacia serotype B and E lipopolysaccharides containing D-fucose, Bioorg. Khim., 14 (1988) 1208-1213. 

Resistance against ascites tumour development and interferon-inducing activity has been demonstrated in the lipopolysaccharide derived from the protein-lipopolysaccharide complex of Pseudomonas aeruginosa Both the lipid A portion and the covalently linked polysaccharide-protein complex appear to be necessary for inhibition of tumour development, whereas the lipid A with amide-linked fatty acid is suficient to induce the in vitro formation of interferon. The lipopolysaccharide of P. aeruginosa has a more pronounced effect as immunogen, mitogen, and interferon inducer than the lipopolysaccharide of Brucella melitensis, although they have similar toxicity levels. Since lipid A is responsible for most of these activities, the variations may be partially explained by structural differences in the lipopolysaccharides. 

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