Lipophilic xenobiotics storage

Table 8.1 represents some of the enzymes (Jakoby and Ziegler, 1990) that participate in altering xenobiotics so as to make them either more readily excretable or less toxic for the storage. These enzymes have a preference for lipophilic compounds, although all hydrophilic compounds, are not excluded. Each enzyme has a phenomenally broad substrate range, and many appear to be inducible. The information for xenometabolism can be obtained from the University of Minnesota Biocatalysis/Biodegradation Database (UM-BBD) at http //umbbd.ahc.umn.edu/ index.html (Ellis et al, 2000). 

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