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Lipophilic drug absorption water-soluble prodrug

On the other hand, highly lipophilic compounds, such as hormones, can be solubilized via the prodrug approach. For example, the rate of transdermal absorption of the highly lipophilic drug, testosterone, was enhanced over 50-fold by forming water-soluble, yet lipophilic, prodrug ester.f The prodrug testoster-onyl-4-dimethylaminobutyrate was found to penetrate human skin tissue, in vitro, 54 times faster than... [Pg.944]

See other pages where Lipophilic drug absorption water-soluble prodrug is mentioned: [Pg.121]    [Pg.182]    [Pg.7]    [Pg.197]    [Pg.1245]    [Pg.1255]    [Pg.824]    [Pg.507]    [Pg.824]   
See also in sourсe #XX -- [ Pg.120 ]



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Absorption solubility

Drug absorption

Drug solubility

Drugs Soluble

Drugs lipophilicity

Lipophilic drug absorption

Lipophilic drug absorption solubility

Lipophilic drugs

Prodrug

Prodrugs soluble

Solubility lipophilicity

Solubility prodrugs

Water absorption

Water absorptiveness

Water-soluble drugs

Water-soluble drugs solubility

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