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Lipids solvent-mediated dispersion

Once the desired mixture of lipid components is dissolved and homogenized in organic solvent, one of several techniques may be used to disperse the liposomes in aqueous solution. These methods may be broadly classified as (1) mechanical dispersion, (2) detergent-assisted solubilization, and (3) solvent-mediated dispersion. [Pg.862]

Solvent-mediated dispersion techniques used to create liposomes first involve dissolving the lipid mixture in an organic solvent to create a homogeneous solution, and then introducing this solution into an aqueous phase. The solvent may or may not be soluble in the aqueous phase to effect this process. There also may be components dissolved in the aqueous phase to be encapsulated in the developing liposomes. [Pg.862]


See also in sourсe #XX -- [ Pg.532 ]

See also in sourсe #XX -- [ Pg.532 ]




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