Lipases phospho

Muscarinic receptors are glycoproteins with molecular weights of approximately 80,000. They are located on the outer surface of the cell membrane, and they are of the G-protein-linked type M, Mg, and Mg receptors couple with proteins to stimulate phospho-lipase-C, whereas Mg and M4 receptors couple with Gi proteins to inhibit adenylate cyclase (25). The molecular basis of muscarinic receptor function has been reviewed (26). Nordvall and Hacksell (27) proposed a molecular model of the transmembrane domains of the receptor, to explain the three-dimensional interaction of the receptor with its ligands. However, the authors specified that the model is "primarily of qualitative value". 

Labourdenne, S., Gaudry-Rolland, N., Letellier, S., Lin, M., Cagna, A., Esposito, G., Verger, R. and Riviere, C. (1994) The oil-drop tensiometer potential applications for studying the kinetics of (phospho)lipase action. Chem. Phys. Lipids 71, 163-173... 

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