Linoleic acid as a substrate

Aspergillus nidulans uses a family of oxygenated long-chain fatty acids called psi factor (precocious sexual inducer), such as psiBa (8-hydroxy-18 2-9,12) and psiCa (5,8-dihydroxy-18 2-9,12) to modulate sexual and asexual spore development. Both hydroxyl fatty acids are produced by cytochrome P450-like fatty acid oxygenases using linoleic acid as a substrate (Tsitsigiannis et al. 2005). 

Fig. 15.56. Competitive inhibition of wheat lipoxy-genase by ascorbic acid (according to Walsh et al., 1970). Activity assay with linoleic acid as a substrate (1) without, and (2) in the presence of ascorbic acid (2 10 mol/l)...

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