Link, Karl

Fig. 10-13. The links between the cycling of C, N, and O2 are indicated. Total primary production is composed of two parts. The production driven by new nutrient input to the euphotic zone is called new production (Dugdale and Goering, 1967). New production is mainly in the form of the upward flux of nitrate from below but river and atmospheric input and nitrogen fixation (Karl et al, 1997) are other possible sources. Other forms of nitrogen such as nitrite, ammonia, and urea may also be important under certain situations. The "new" nitrate is used to produce plankton protoplasm and oxygen according to the RKR equation. Some of the plant material produced is respired in the euphotic zone due to the combined efforts...

Karl Von Eckartshausen Was Among the Most Unusual Mystics of His Day. He Was Both a Fervent Catholic and a Theosophist in the Tradition of Jacob Boehme. A Convinced Believer in the "Interior Church" That Mystical Body of True Believers, Linked by Spiritual Experience Rather Than by Doctrine, Eckartshausen Sought to Broadcast His Unique Understanding of the Way of Regeneration in Christ. In The Cloud Upon the Sanctuary, He... 

Karl grew up in a stimulating family environment with five brothers and four sisters, all of whom entered professional or business careers, or gave their time freely to service activities. While he was still in high school, Karl s aptitude for chemistry revealed itself—when the chemistry teacher was called away for service in the First World War, Karl was asked to teach his fellow students until a new teacher could be found. His choice to study Agricultural Chemistry in the University appears to have been determined in part by finances, because Link once said that, if he had had just a bit more money, he would have entered Medical School. 

In retrospect, it seems probable that the medical profession gained far more from Link s successes as an agricultural chemist than it could have from his practice of medicine. The discovery of Dicumarol and its adoption as an important clinical anticoagulant, and the synthesis of Warfarin and its development as a widely used rodenticide—these accomplishments, which will not be described in this article, alone were more than sufficient to make Karl Link an important name in science. For his work on Dicumarol, Link received the Cameron Award from the University of Edinburgh in 1952, the Lasker Award in 1955 and 1960, the John Scott Award in 1959, and the Kovalenko Medal of the National Academy of Sciences in 1967. He was a Harvey Lecturer... 

How are Karl Link s contributions to the field of carbohydrate chemistry to be judged, what was his professional standing, and how did he influence developments in the field Fundamentally, he was interested in natural products from the viewpoint of an organic chemist, but he never considered himself to be a modem organic chemist, and he appears to have made little effort to apply the tools of physical organic chemistry to carbohydrates. Link did not often go to... 

It is not a happy moment when writing on the passing of a close friend, colleague, and mentor. In this instance, the sadness is tempered by the recognition that Karl Link had a long, creative, produc-... 

This proposal supported, with an earlier prediction of Sir Robert Robinson, that cholesterol was a cyclization product of squalene, a 30-carbon polymer of isoprene units. In 1953, Robert Bums Woodward and Bloch postulated a cyclization scheme for squalene (fig. 20.2) that was later shown to be correct. In 1956, the unknown isoprenoid precursor was identified as mevalonic acid by Karl Folkers and others at Merck, Sharpe, and Dohme Laboratories. The discovery of mevalonate provided the missing link in the basic outline of cholesterol biosynthesis. Since that time, the sequence and the stereochemical course for the biosynthesis of cholesterol have been defined in detail. 

This brochure was mainly written by me (under four pen names), but made fit for publication by Karl Philipp, who made some changes to it and chose Remer as editor and publisher to protect me legally (which worked). As far as I know, Remer was not involved in the actual production of the brochure, and I was never involved in its distribution. Therefore, no link ever existed between my writing the brochure—without any intention to do it for Remer—and the fact that Philipp put Remer s name on it (probably even without Remer knowing it) after I had finished my writings. True, I never complained about it, but there was, realistically seen, no other way than Philipp s way to have this brochure published swiftly—winch was necessary since it was a reaction to a series of articles in a weekly newspaper—, and I did not intend to reveal my pen names to anybody anyway, so why bother ... 

Last, J.A. (2002). The missing link the story of Karl Paul link. Toxicol. Sci. 66(1) 4-6. 

Zehr, J. P., Montoya, J. P., Jenkins, B. D., Hewson, I., Mondragon, E., Short, C. M., Church, M. J., Hansen, A., and Karl, D. M. (2007). Experiments linking nitrogenase gene expression to nitrogen fixation in the North Pacific subtropical gyre. Limnol. Oceanogr. 52, 169—183. 

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