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Light scatter detection method

HALS presents some analytical difficulties. Coulier et al. [18] describe a pyrolysis GC-MS method for identification and HPLC with UV and evaporative light scattering detection methods for quantification in polymer extracts. [Pg.594]

In the large off-axis light scatter detection method, the droplet size can be related, for example, to the phase shift of the light scattered by refraction in the off-axis forward direction as ... [Pg.417]

Sarri, A.K., Megoulas, N.C., and Koupparis, M.A. Development of a novel liquid chromatography evaporative light scattering detection method for bacitracins and applications to quality control of pharmaceuticals. Anal. Chim. Acta 2006, 573,... [Pg.92]

Schnabel, W. (1979) Application of the light scattering detection method to problems of polymer degradation, in Developments in Polymer Degradation - 2 (ed. N. Grassie), Applied Science Publishers, London, Ch. 2. [Pg.321]

Recently, Caco-2 permeability screening has been optimized to accommodate the increasing demand for permeability assessment. Analytical methods like HPLC coupled with UV, evaporative light scattering detection (ELSD), or fluorescence detection were used traditionally... [Pg.421]

Liu CZ, Zhou HY, Zhao Y. (2007) An effective method for fast determination of artemisinin in Artemisia annua L. by high performance liquid chromatography with evaporative light scattering detection. Anal Chim Acta 581 298-302. [Pg.331]

Capillary SFC is particularly useful for compounds that are difficult to detect using LC and too unstable for GC. Nevertheless, at present there have not been enough applications to justify an investment (74, 75). In contrast, packed-column SFC has undergone a renaissance thanks to evaporative light-scattering detection (ELSD). Packed-column SFC-ELSD is a suitable method for analyzing various compounds, with or without chromophores, and with diverse polarities, as found in drug, steroid, and ionophore complex mixtures (76-79). [Pg.678]

BS Lutzke, JM Braughler. An improved method for the identification and quantitation of biological lipids by HPLC using laser light scattering detection. J Lipid Res 31 2127-2130, 1990. [Pg.283]

NU Olsson, AJ Harding, C Harper, N Salem Jr. High performance liquid chromatography method with light scattering detection for measurements of lipid class composition analysis of brains from alcoholics. J Chromatogr B 681 213—218, 1996. [Pg.283]

Another detection scheme for carbohydrate analysis was used by Guo et al. [113]. The coupling of condensation nucleation light-scattering detection with pressurized CEC was investigated. The method afforded the separation of sucrose and saccharin with high sensitivity and no derivatization was required. [Pg.391]

Choice of the proper detection scheme is dependent on the properties of the analyte. Different types of detectors are available such as ultraviolet (UV), fluorescence, electrochemical, hght scattering, refractive index (RI), flame ionization detection (FID), evaporative light scattering detection (ELSD), corona aerosol detection (CAD), mass spectrometric (MS), NMR, and others. However, the majority of reversed-phase and normal-phase HPLC method development in the pharmaceutical industry is carried out with UV detection. In this section the practical use of UV detection will be discussed. [Pg.367]

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