Ligand binding ionic

Studies of CpLi solutions showed high conductivity, suggesting ionic particles in solution.91 Ionic particles could consist of the free ions, but anionic cyclopentadienides MCp2- particles isoelectronic to the well-known alkaline earth cyclopentadienides Cp2M (M = alkaline earth metal),103 could also be envisioned. Moreover, the structural motif of a sandwich complex where two Cp ligands bind to a metal center is well established throughout the periodic table. Indeed, the Cp2 Li anion was suggested based on NMR techniques,114-116 and... 

Elution is one of the critical step for successful separation. Sample application in affinity chromatography is performed usually by injection or application in the presence of mobile phase which is prepared in appropriate pH, ionic strength and solvent composition for solute-ligand binding. This solvent is referred as application buffer [8]. In the presence of application buffer, compounds which are complementary to the affinity ligand will bind while the other solutes in the sample will tend to pass through the column as nonretained compounds. After... 

Let us consider the [2+2] macrocyclic ligand 6.39, which is prepared by the non-template condensation of 1,2-diaminobenzene with 2,6-diformylpyridine. The hole size of this ligand is about 1.3 A, so we would expect it to be too large to bind first-row transition metal dications. As a matter of interest, the ligand binds K+, with an ionic radius of 1.38 A, more strongly than does the crown ether, 18-crown-6. In the absence of any che-... 

F. 9a-g. Types of binding interactions that can be exploited during templating a n-n interaction b hydrophobic or van der Waals interaction c covalent bonds d (transition) metal-ligand binding e hydrogen bonding f crown ether -ion interaction g ionic interaction... 

---