Ligand binding G proteins

When epinephrine occupies its receptor it activates the ligand binding/ G-protein/ adenylate cyclase cascade. This in turn phosphorylates the muscle enzyme, phosphorylase. This form of the enzyme is the active form which cleaves glucose 1-phosphate unit from glycogen, eventually depleting it... 

Evers, A., Hessler, G., Matter, H. and Klabunde, T. (2005) Virtual screening of biogenic amine-binding G-protein coupled receptors comparative evaluation of protein- and ligand-based virtual screening protocols. 

We can observe experimental evidence of alternative products, profiles, binding ligands, and G-proteins. 

Royer, C.A., Tauc, P., Herve, G. and Brochon, J.-C. (1987). Ligand binding and protein dynamics a fluorescence depolarization study of aspartate transcarbamylase from Escherichia coli. Biochemistry, 26, 6472-6478. 

Whereas those technologies have been applied and optimised over the last decade to investigate binding events of relative large binding partners on typically surface immobilised ligands (e.g. protein-protein or antigen-antibody... 

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