Levamisole Warfarin

LEVAMISOLE ANTICOAGULANTS -WARFARIN Possible t anticoagulant effect Uncertain Monitor INR closely... 

Levamisole and 5-fluorouracil interact with warfarin to produce bleeding (58). The mechanism of this effect is unclear, but the reports are sufficiently clear to point to the need for careful monitoring when this drug combination is used. 

Wehbe TW, Warth JA. A case of bleeding requiring hospitalization that was likely caused by an interaction between warfarin and levamisole. Chn Pharmacol Ther 1996 59(3) 360-2. 

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