Leishmaniasis clinical manifestations

Leishmaniasis affects some 12 million humans aimuaHy ia an area where 350 million are at risk. It is a complex of at least two protozoan diseases, consisting primarily of cutaneous and visceral forms. A mucocutaneous form is considered by some to be another distinct variety. Clinical manifestations of the disease range from an asymptomatic infection to an infection ia which there is considerable destmction of cutaneous tissue and mucous membranes. Leishmaniasis can often be fatal, especially ia the visceral form. The seriousness of the disease depends on the state of the immunological system of the... 

Leishmaniasis presents as a variety of clinical manifestations - from cutaneous lesions to the visceral form, with the latter being fatal if untreated. The disease is caused by Ldshmania species (e.g., L. major or L. infantum) these intracellular pathogens are widespread over Africa, Asia, and South America, and worldwide... 

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