Ledderhose Disease

Plantar fibromatosis is a benign condition characterized by focal nodular enlargement of the plantar aponeurosis due to local proliferation of fibrous tissue. Its origin is unknown and it was first described by Dupuytren in 1839, who noted an association with palmar fibromatosis (Dupuytren 1839). This condition is also known as Ledderhose disease after the eponymous doctor who reported more than 50 cases in 1897 (Ledderhose 1897). Patients present with... 

The incidence of barbiturate-induced Dupuytren s contracture, frozen shoulder, Ledderhose syndrome, Peyronie s disease, fibromas, and joint pains may be up to 10% (6). Most affected patients develop connective tissue changes in the first year, although these become disabling at a later stage. These complications should be recognized early, since they are often reversible (SED-12, 137) (7). 

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