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Large Scale Biology Company

A highly optimized and concise large-scale synthesis of a purine bronehodilator was developed by the Astra Production Chemical company from Sweden [6], Supplies for the initial biological studies were generated by the medieinal ehemistry route shown in Scheme 5. The overall yield was about 14%, which was improved in the environmentally friendly manufacturing process to about 51% (Seheme 6 and Scheme 7). [Pg.242]

Large-scale collaborations between pharmaceutical companies and academia are largely a phenomenon of biology and pharmacology (5 11). Although these agreements may represent extensive support and collaborative opportunities for the faculty involved, they are relatively infrequent. Table 9-2 lists the bulk of such relationships of direct or indirect relevance to the pharmaceutical industry. In some cases, the industrial partner may create an entire physical structure in which industrially-supported work... [Pg.208]

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See also in sourсe #XX -- [ Pg.127 ]



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