Lantibiotics, characteristics

The inability to obtain complete protein sequence analysis of purified bacteriocins has been reason to suspect the presence of N-blocked peptide sequences (34) or lantibiotic residues (14). Recently, Piard et al. (14) have shown from partial sequencing and composition analysis that lacticin 481, a broad spectrum bacteriocin produced by L. lactis 481, also contains lanthionine residues. The early widespread interest in nisin and nisin-producing strains had given the impression that lantibiotics may be characteristic of bacteriocins of lactic acid bacteria. However, recent studies with other LAB bacteriocins suggest that simple peptide bacteriocins may prevail among the LAB. 

Tabic 2 Characteristics of Predicted Gene Products in Lantibiotic Gene Clusters... 

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