Lansoprazole Vecuronium

VECURONIUM PROTON PUMP INHIBITORS -LANSOPRAZOLE Possible t efficacy and adverse effects of vecuronium Unclear Altered duration of action. May need t recovery time... 

There is some evidence that lansoprazole increases the duration of action of vecuronium. 

In a study of 50 adult surgical patients, half of whom received lansoprazole 30 mg on the night before their operation, it was found that there was no significant difference between the time of onset of neuromuscular blockade by vecuronium in the two groups, but lansoprazole increased the duration of effect by about 34%. This needs confirmation but be alert for this interaction in any patient treated with lansoprazole. 

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See also in sourсe #XX -- [ ]

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