Langley, John Newport

Langley, John Newport, 2-3, 3f Langmuir, Irving, 10, 12f Langmuir adsorption isotherm... 

Previously, in animal experiments in the 1870s, John Newport Langley, Professor of physiology in Cambridge (UK) had shown that jaborandi extract, containing pilocarpine, modified the heart rate, the effect being reversed by atropine. Similarly, pilocarpine stimulated the secretion of saliva and atropine inhibited it. In both heart and salivary gland experiments, the effect depended on the amount of... 

In 1905, John Newport Langley (1852-1925) reported on his experiments, carried out at Cambridge University, with nicotine and curare on the skeletal muscles of frogs and chickens, where he formulated the concept of cellular receptive substances (we would say structures ), which mediate the activity of these agents. [123] This represents the actual foundation of a neuronal receptor theory (Fig. 8.32), and led Paul Ehrlich two years later to propose more generally the existence of chemoreceptors for drugs. 

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