L-2,4-Diaminobutanoic acid

A structure somewhat related to the acyl phosphonate analogue (VIII.83) has been briefly described [278] in a report on FPGS inhibitors. The preparation of this compound (VIII.86) was achieved from V -(4-amino-4-deoxy-V °-methylpteroyl)-L-lysine and 4-nitrophenyl phosphonoacetate. While (VIII.86) obviously contained too many CH2 groups to be considered a close analogue of (VIII.83), the shorter-chain compound (VIII.87), a derivative of V -(4-amino-4-deoxy-V °-methylpteroyl)-L-2,3-diaminobutanoic acid, would seem to be reasonable candidate for this role. 

Diaminobutanoic acid methyl ester, L Ornithine methyl ester, L Lysine methyl ester, L... 

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