L-Chloro-2-fluoroethane

All the toxic compounds mentioned above are either hydro-lysable or oxidizable to fluoroacetic acid.1 In this connexion it should be noted that l-chloro-2-fluoroethane was relatively nontoxic. The chlorine atom in this compound was shown to be rather unreactive chemically, hence hydrolysis to the toxic fluoroethanol in the animal body would be unlikely. 

Subsequently, the ethylenechloronium ion 158-C1 was obtained.387 When, instead of SO2, SO2CIF was used as the solvent in the reaction of antimony pentafluoride with l-chloro-2-fluoroethane at — 80°C, a solution was obtained whose 1H NMR spectmm consisted of these absorptions a doublet (81H 4.6, 3H,./ 6 Hz), a quartet (8 H 13.3,... 

Reaction between l-Chloro-2-fluoroethane and Ethyl Acetoacetate... 

FIGURE 6 Fluorine spectra at 56.4 MHz of 1,1,2,2-tetrabromo-l-chloro-2-fluoroethane. Left, experimental spectra as a function of temperature. Right, calculated spectra as a function of mean lifetime before rotation (seconds). (See caption to Figure 5.)... 

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