Werner Kuhn

N. Avril, S. Sassen, B. Schmalfeldt, J. Naehrig, S. Rutke, W.A. Weber, M. Werner, H. Graeff, M. Schwaiger, W. Kuhn, Prediction of response to neoadjuvant chemotherapy by sequential F-18-fluorodeoxyglucose positron emission tomography in patients with advanced-stage ovarian cancer, J. Clin. Oncol. 23(30) (2005) 7445-7453. 

One can use another way to describe the long macromolecule. One can see that at high temperatures there is no correlation between the orientations of the different parts of the macromolecule, which are not close to each other along the chain. This means that the chain of freely-jointed rigid segments reflects the behaviour of a real macromolecule. This model carries the name of Werner Kuhn who introduced it in his pioneering works (Kuhn 1934). 

Werner Wenning, Chmn.-Mgmt. Board Klaus Kuhn, CFO... 

Danel VC, Saviuc PF, Garon D. Main features of Cortinarius spp. poisoning a literature review.Toxicon 2001 39 1053-1060 Prast H, Werner ER, Pfaller W, Moser M. Toxic properties of the mushroom Cortinarius orellanus. I. Chemical characterization of the main toxin of Cortinarius orellanus (Fries) and Cortinarius speciosissimus (Kuhn Romagn) and acute toxicity in mice. Arch Toxicol 1988 62 81-88... 

It is also possible to envision a bridging intermediate for transfer of 7t-allyl groups. A model structure comes from the studies of Werner and Kuhn (19,20), who found that the reaction of i 3-allyl- 5-cyclopentadienyl palladium with tertiary phosphines led to dinuclear complexes having the general structure 3. X-Ray analysis verified the structure. The platinum analog could also be prepared. 

Much as he would like to claim it for his own, the viewpoint just set forth is not original with the present author. It is already implicit in the classical work of Werner Kuhn, . a man far ahead of his time in the field of optical activity, and it may also be found to varying degrees in the work of Condon, Eyring, > > Kauz-mann, Moffitt, > > and others. What makes it so timely now is that experimentalists such as Djerassi and Klyne, taking advantage in their work of the recent advances in polari-metric instrumentation, have stimulated theoretical progress to the point where it is possible, within limits, to feasibly characterize the optical activity associated with a particular electronic transition in terms of experimentally accessible parameters. And it can be shown that these parameters, which are of much the same kind that one encounters in ordinary optical absorption spectroscopy, do contain important molecular information that is unavailable elsewhere. 

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