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Kidney specific gene targeting

Knockout" mouse models Compensatory responses Strain differences Gender differences Kidney Specific Gene Targeting Types of renal injury ischemic Nephrotoxic Septic... [Pg.173]

Igarashi Kidney-specific gene targeting. J.Am.Soc.Nephrol. 15 2237-2239,2004... [Pg.207]

Linehan WM, Pinto PA, Srinivasan R, et al. Identification of the genes for kidney cancer opportunity for disease-specific targeted therapeutics. Clin Cancer Res. 2007 13 671s. [Pg.659]

Meanwhile, the intravenous delivery of lipid-entrapped pDNA was shown to efficaciously lead to gene expression, especially in liver, lung, and kidneys [100]. The addition of targeting molecules can efficiently target the vesicles to specific cells. For example, the utilization of galactosyl-cholesterol or mannosylated-... [Pg.1000]

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Gene targeting

Target specifications

Target-specific

Targeting specificity

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