Ketose reductase

In clinical chemistry however, these systems have not been differentiated as yet. Since the oxidation of an alcohol corresponds to the reduction of a ketose or an aldose, the designations ketose reductase and aldose reductase, respectively, were suggested (H4, W14). In this paper however, the enzyme or enzyme system will be named polyol or sorbitol dehydrogenase (SDH), although the latter expression does not characterize exacdy the enzyme s function in a general biochemical sense. But sorbitol or fructose have been commonly used as substrates in clinical chemical investigations. 

W14. Williams-Ashman, H. G., and Banks, J., The ketose reductase of rat liver and accessory sexual organs. Arch. Biochem. Biophys. 50, 513-515 (1954). 

Silverleaf whitefly ketose reductase 1E3J CysL 2 CySba 2 CySa 7 Cys... 

B. Hafliger, E. Kindhauser, and F. Keller, Metabolism of D-glycero-D-manno-heptitol, volemitol, in Polyanhus. Discovery of a novel ketose reductase, Plant Physiology, 119 (1999) 191-197. 

Aldose-ketose interconversions 692 Aldose reductase 774 Algae 20-22 Algin 21... 

Aldose reductase has been utilized for the selective reduction of aldos-2-uloses to 2-ketoses. Singlet oxygen oxidation of alditol-1-C-ylfurans 8 has afforded quantitative yields of enosuloses 9. Conjugate addition to enone 10 readily afforded the 2-deoxy-a-hexos-3-ulosides 11 and thioglycosidic analogues." l-C-(2-Thiazolyl)-... 

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