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Ketone reaction with LDA

For unsymmetrical ketones, reactions with LDA at low temperature favor formation of the kinetic enolate, while reactions with NaH at room temperature favor the thermodynamic enolate. [Pg.1079]

See also in sourсe #XX -- [ Pg.861 ]

See also in sourсe #XX -- [ Pg.861 ]

See also in sourсe #XX -- [ Pg.713 ]

See also in sourсe #XX -- [ Pg.888 ]

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LDA

Reaction with LDA

Reaction with ketone