Kaolin Propranolol

The absorption of some drugs may also be reduced if they are given with adsorbents such as charcoal or kaolin, or anionic exchange resins such as colestyramine or colestipol. The absorption of propranolol, digoxin, warfarin, tricyclic antidepressants, ciclosporin and levothyroxine is reduced by colestyramine. 

KAOLIN BETA-BLOCKERS Possibly 1 levels of atenolol, propranolol and sotalol 1 absorption Separate doses by at least 2 hours... 

Aluminium hydroxide gel 30 mL did not affect the plasma level of a single 40-mg dose of propranolol in 6 healthy subjects the reduction in exercise heart rate was also unaffected. In contrast, a study in 5 healthy subjects found that 30 mL of an aluminium hydroxide gel reduced the levels and AUC of a single 80-mg dose of propranolol by almost 60%. In vitro and animal data suggest that bismuth subsalicylate, kaolin-pectin and magnesium trisilicate can also reduce the absorption of propranolol. ... 

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