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Isosterism and bioisosterism

Burger, A. (1991) Isosterism and bioisosterism in drug design. Prog. Drug Res. 2>1, 287-371. [Pg.437]

The following Case Studies show several examples of isosteres and bioisosteres in use. The story of the development of cimetidine also demonstrates the use of chain homologation. [Pg.283]

As the distinction between isosteres and bioisosteres is rather of academic interest, it is preferred, in this chapter to treat both categories together. Conseqnently, for example, divalent series snch as 0=, HN=, and H2C= can be discussed together with S=. However, the correct nomenclature will be used as much as possible, keeping in mind nevertheless that isosteric replacement embraces both true isosteres and bioisosteres. [Pg.294]

Functional Group Modification Isosterism and Bioisosterism Isosterism... [Pg.92]

See other pages where Isosterism and bioisosterism is mentioned: [Pg.273]    [Pg.290]    [Pg.294]    [Pg.295]    [Pg.297]    [Pg.299]    [Pg.301]    [Pg.303]    [Pg.305]    [Pg.307]    [Pg.309]    [Pg.311]    [Pg.313]    [Pg.315]    [Pg.317]    [Pg.319]    [Pg.321]    [Pg.341]    [Pg.189]    [Pg.192]    [Pg.2]    [Pg.46]    [Pg.324]    [Pg.290]    [Pg.294]    [Pg.295]    [Pg.297]    [Pg.299]    [Pg.301]    [Pg.303]    [Pg.305]    [Pg.307]    [Pg.309]    [Pg.311]    [Pg.313]    [Pg.315]    [Pg.317]    [Pg.319]    [Pg.321]   
See also in sourсe #XX -- [ Pg.2 ]



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Bioisostere

Bioisosteres

Bioisosteres/bioisosterism

Bioisosteric

Bioisosterism

Encountered Isosteric and Bioisosteric Modifications

Isostere

Isosteres

Isosteric

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