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5-isosorbide mononitrate ISMN

Isosorbide Dinitrate (ISDN) and Isosorbide Mononitrate (ISMN)... [Pg.311]

Fig. 10.6 Schematic diagram of proposed mechanisms by which NO-containing molecules relax vascular smooth muscle (redrawn and modified after Van de Voorde 1991 [7]). NTG, nitroglycerin R-0-N02, organic nitrate ISDN, isosorbide dinitrate ISMN, isosorbide mononitrate R -SH and R"-SH, thiol-containing molecules R -S-S-R disulfides R-OH,... Fig. 10.6 Schematic diagram of proposed mechanisms by which NO-containing molecules relax vascular smooth muscle (redrawn and modified after Van de Voorde 1991 [7]). NTG, nitroglycerin R-0-N02, organic nitrate ISDN, isosorbide dinitrate ISMN, isosorbide mononitrate R -SH and R"-SH, thiol-containing molecules R -S-S-R disulfides R-OH,...
The oldest class of clinically used NO donors are the organic nitrates (R-ONO2) (Fig. 20.3), which are nitric acid esters of mono and polyhydric alcohols, including glyceryl trinitrate (GTN A.l), pentaerithrityl tetranitrate (PETN A.2), isosorbide dinitrate (ISDN A.3), and isosorbide-5-mononitrate (ISMN A.4). Metabolites of GTN, viz., glyceryl mononitrate (GMN) and glyceryl dinitrate (GDN), are pharmacologically active, but less potent than GTN. [Pg.366]

ISMN) determine plasma levels of isosorbide 5-mononitrate... [Pg.274]

See other pages where 5-isosorbide mononitrate ISMN is mentioned: [Pg.120]    [Pg.124]    [Pg.913]    [Pg.148]    [Pg.120]    [Pg.124]    [Pg.913]    [Pg.135]    [Pg.380]    [Pg.281]    [Pg.216]    [Pg.413]    [Pg.354]    [Pg.110]   
See also in sourсe #XX -- [ Pg.120 ]



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Dinitrate (ISDN) and Isosorbide Mononitrate (ISMN)

Isosorbid

Isosorbide

Isosorbide mononitrate

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