Isoquinolines nitro-, oxidative amination

Oxidative aminations are possible at other quinoline and isoquinoline positions, even on the benzene ring, providing a nitro group is present to promote the nucleophilic addition ... 

Ethan l-Acetamino-l-(4-methyl-phenyl)-2-nitro- E16d, 162 (En + NOf + R-CN) Hydroxylamin l-(4-Nitro-phenoxy)-E16a, 306 (Amin-oxid-Umlager.) Isoquinolin l-Hydroxyamino-5,6-methylendioxy-2-methyl-l, 2,3,4-tetrahydro- E16a, 13 (OH - NH-OH)... 

---