Isoproterenol applications

In these last months some applications of the electrostatic molecular potential approach have been performed. Such studies concern -adrenergic drugs and psycotomimetic cholinergic agents. In the first family, compounds like isoproterenol and INPEA have been examined in the CNDO approximation 79>80>. in the second family a large set of com-... 

M40 Mitova, M. and Bednafik, B. Influencing heart necroses caused by application of isoproterenol, potassium orotate. Scr. Med. Fac. Med. Univ. Brun. Purkynianae, 49, 259-263 (1976)... 

The topical application of 0.1 mM norepinephrine has been shown by Segal (1981) to cause a 3-4-mV hyperpolarization of CAl neurons of the rat hippocampal slice associated with a 10-20% decrease in input resistance (Fig. 31). The time course of the potential and resistance changes evoked by norepinephrine were substantially slower than those evoked by GABA and 5-HT on other cells in the same slice preparation. The hyperpolarization evoked by norepinephrine was mimicked by isoproterenol and... 

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