Iso-Propylamine

Chemical Designations - Synonyms 2-Aminopropane Monoisopropylamine iso-Propylamine Chemical Formula (CH3)2CHNHj. 

A mixture of 2 parts of 1-(4-acetamidophenoxy)-2,3-epoxypropane and 10 parts of iso-propylamine is stirred at ambient temperature for 16 hours. The resulting solution is... 

Hexane-free LDA was prepared by the dropwise addition of n-BuLi in hexane (leq, 2.4m) to a stirred solution of di-isopropylamine (1.5eq.) in hexane (ca. 2m) at 0°C. After complete addition, the viscous mixture was stirred for a further lOmin, after which time the hexane and excess di-iso-propylamine were removed under reduced pressure at 0°C. The resulting white solid was redissolved in sufficient THF at 0 °C to give an approximately 0.3 M solution. 

Jacob, P., Ill, and Shulgin, A. T. (1983) Sulfur analogues of psychotomimetic agents. 2. Analogues of (2,5-dimethoxy-4-methylphenyl) and (2,5-dimethoxy-4-ethylphenyl)iso-propylamine. J. Med. Chem., 26 746-752. 

It has been recently reported that, contrary to previous assumptions, primary steric effects due to a branching in the amine do not produce a large decrease in the reaction rate when the first step is rate-determining82. In Sat Ar reactions of amines with fluoronitroben-zene, it is generally accepted that the second step of the mechanism depicted in Scheme 1 is rate-determining base catalysis is frequently found and the observed rate constants obey equation 2. Nevertheless, the reaction of o-fluoronitrobenzene with n- and iso-propylamine in toluene and in DMSO are only slightly sensitive to the nucleophile concentration. The... 

Other clear-cut evidence that the dichotomy between primary and secondary amines cannot be due to differential steric compression in the tr-complexes formed in these reactions has been afforded by Nudelman and Cerdeira82 in their study of the reactions of o-and p- lluomn i Irobenzenes with two primary amines n- and iso-propylamine in... 

Metaproterenol Metaproterenol, a-[(isopropylamino)methyl]-3,5-dihydroxybenzylic alcohol (11.1.15), is an analogue of terbutaline, in which the tert-butylamine group is replaced with an iso-propylamine group. Synthesis is accomplished in the same manner as terbutaline synthesis [19-21]. 

The second method nses the same reagents in the presence of a base and consists of initially making 3-(l-naphthyloxy)propylenoxide (12.1.3), the snbseqnent reaction with iso-propylamine which resnlts in epoxide ring opening leading to the formation of propranolol (12.1.2) [1-6]. 

ISOPROPYLAMINE 2-Aminopropane, Monoisopropyl-amine, iso-Propylamine Flammable Liquid, I 3 4 0... 

Among these amines, iso-propylamine was the most suitable for this process, because it was released from 7 during the C-C bond-forming reaction as a byproduct and was able to be reused for the CIDT without adding any additional amine. In fact, vacuum concentration of the C-C bond-forming reaction mixture left a catalytic amount of iso-propylamine in the residue, and the residual isopropylamine effectively catalyzed CIDT without the addition of further amine to afford threo-8 in 89% yield with >99% dr. The level of residual iso-propylamine was... 

It was prepd by heating iso propylamine with tetranitrobiphenol in ale in a sealed tube at 100°(Refs 2 4). It can be nitrated to a hexanitro deriv (qv)... 

Iso-Propylamine shows the same behavior as the normal compound. 

Figure 8. Comparison of gel permeation chromatograms of basic fractions (A-15) of (a) Athabasca asphaltenes and (b) resins Bz - benzene MeOH = methanol iPrN - iso-propylamine nC5 - n-pentane PhMe and PS (15,000) - VR of toluene and Vo, respectively...

Fig. 10. The influence of primary amines on the oxidation of acetaldehyde at 124 C [69, 71]. Acetaldehyde pressure 100 torr oxygen pressure 100 torr. (a) No amine added (b) 0.95 torr methylamine (c) 1.79 torr ethylamine (d) 2.27 torr n-butyl-amine (e) 2.56 torr ferf-butylamine (f) 2.22 torr iso-propylamine.

Fig. 16. The variation of Pmaxi the maximum rate of oxidation in torr. min of some primary and secondary aliphatic amine with temperature [114], Amine pressure 500 torr oxygen pressure 200 torr. , Methylamine , ethylamine , iso-propylamine B, dimethylamine o, w-propylamine , di-iso-propylamine a, ethylmethyl-amine , iso-butylamine , n-butylamine , diethylamine , methyl-n-propylamine di-n-propylamine , n-butylchloride.

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