Iron sulfur clusters biosynthesis

Agar JN, Krebs B, Frazzon J, et al. 2000a. IscU as a scaffold for iron-sulfur cluster biosynthesis sequential assembly of [2Fe-2S] and [4Fe S] clusters in IscU. Biochemistry 39 7856-62. 

Nuth M,YoonT, Cowan JA. 2002. Iron-sulfur cluster biosynthesis Characterization of iron nucleation sites for the assembly of the [2Fe-2S] cluster core in IscU proteins. J Am Chem Soc 124 8774-5. 

Smith AD, Agar JN, Johnson KA, et al. 2001. Sulfur transfer from IscS to IscU The first step in iron-sulfur cluster biosynthesis. J Am Chem Soc 123 11103-4. 

Wu S-P, Wu G, Surerus KK, Cowan JA. 2002c. Iron-sulfur cluster biosynthesis Kinetic analysis of [2Fe-2S] cluster transfer from holo ISU to apo Fd Role of redox chemistry and a conserved aspartate. Biochemistry 41 8876-85. 

LaGier MJ, Tachezy J, Stejskal F, Kutisova K, Keithly JS (2003) Mitochondrial-type iron-sulfur cluster biosynthesis genes (IscS and IscU) in the apicomplexan Cryptosporidium parvum. Microbiology 149 3519-3530... 

Iron-Sulfur Cluster Biosynthesis and the Evolution of Mitochondria... 

Keithly JS, Langreth SG, Buttle KF, Mannella CA (2005) Electron tomographic and ultrastruc-tural analysis of the Cryptosporidium parvum relict mitochondrion, its associated membranes, and organelles. J Eukaryot Microbiol 52 132-140 LaGier MJ, Tachezy J, Stejskal F, Kutisova K, Keithly JS (2003) Mitochondrial-type iron-sulfur cluster biosynthesis genes (IscS and IscU) in the apicomplexan Cryptosporidium parvum. Microbiology 149 3519-3530... 

Majumder K, Bhattacharya S (1999) Amino acid complexes of ruthenium synthesis, characterization and cychc voltammetric studies. Polyhedron 18 3669-3673 Makosza M (2000) Phase transfer catalysis a greener methodology for organic synthesis. Pure Appl Chem 72 1439-1445 Mansy SS, Cowan JA (2004) Iron-sulfur-cluster biosynthesis toward an understanding of cellular machinery and molecular mechanism. Acc Chem Res 37 719-725 Marker B (1994a) The biological system of the elements (BSE) for terrestrial plants (glycophytes). Sci Total Environ 155 221-228... 

In bacteria, coenzyme biosynthesis is located in the cytoplasm. In eukaryotic cells, organelles play important roles in the biosynthesis of certain cofactors. For example, certain steps of iron/sulfur cluster biosynthesis proceed in mitochondria... 

The enzymology of ThiS-COSH formation is shown in Figure 6. Adenylation of ThiS-COOH (5) is catalyzed by ThiF. The resulting acyl-adenylated 6 reacts with the IscS persulfide, a species also involved in iron—sulfur cluster biosynthesis, to form the mixed acyl disulfide 25. This is then reduced to give ThiS-COSH (3). " The enzymology of this reduction has not yet been determined. The ThiFS complex has been structurally characterized. ... 

S.S. Mansy and J.A. Cowan (2004) Accounts of Chemical Research, vol. 37, p. 719 - Iron-sulfur cluster biosynthesis toward an understanding of cellular machinery and molecular mechanism . 

Shimomura Y, Wada K, Fukuyama K, Takahashi Y The asymmetric trimeric architecture of [2Fe-2S] IscU Implications for its scaffolding during iron-sulfur cluster biosynthesis. J Mol Biol 2008, 383(1) 133—143. 

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