Iron-DOPA interaction

There are problems as well in the absorption of certain drugs in the presence of specific food components. L-Dopa absorption may be inhibited in the presence of certain amino acids formed from the digestion of proteins [43], The absorption of tetracycline is reduced by calcium salts present in dairy foods and by several other cations, including magnesium and aluminum [115-117], which are often present in antacid preparations. In addition, iron and zinc have been shown to reduce tetracycline absorption [118], Figure 17 illustrates several of these interactions. These cations react with tetracycline to form a water-in-soluble and nonabsorbable complex. Obviously, these offending materials should not be co-administered with tetracycline antibiotics. 

Roberto, 2007). The bioadhesive of Mytilus califomianus is slightly diflPerent from that of M. edulis (Holten-Andersen, Zhao, and Waite, 2009). Interactions between Dopa and iron into Fe(dopa)3 complexes, may improve the hardness and extensibility of byssus threads (Wilker, 2010) (Figure 18.3). 

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