Ipratropium bromide anhydrous

Since water molecules occupy regular positions within the lattice of a hydrate with a specific stoichiometry (e.g., 1 1 monohydrate, 2 1 dihydrate, 5 1 pentahydrate) to the solid, relatively large quantities of water are sorbed. Figure 3 shows a moisture uptake isotherm for ipratropium bromide [39]. This substance undergoes an apparent hydration of the crystal between 63% and 75% relative humidity. Above 75% relative humidity, approximately 4.6% water is sorbed (theoretical monohydrate is 4.4 g/g). Interestingly, as anhydrous ipratropium bromide is equilibrated for extended time periods (e.g., 2 months and 5 months respectively, as shown in Fig. (3), hydration of the crystal appears to occur at... 

Atrovent inhalation solution is administered by oral inhalation with the aid of a nebulizer. It contains ipratropium bromide 0.02% (anhydrous basis) in a sterile, isotonic... 

Atrovent (ipratropium bromide) Nasal Spray 0.03% is a metered-dose, manual-pump spray unit that delivers 21 meg (70, uL ) ipratropium bromide per spray on an anhydrous basis in an isotonic, aqueous solution with pH... 

Atrovent HFA (BI) Ipratropium bromide November 2004 HFA 134a, purified water, dehydrated alcohol, anhydrous citric acid Solution... 

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See also in sourсe #XX -- [ ]

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