Iodo-2-methyl-propane

Between system 7090 and 7091, omit A = C4H9I l-Iodo-2-methyl propane. 

C4H203 maleic anhydride 108-31-6 5.960E+09 44.040 3669 C4H9I 2-iodo-2-methyl propane 558-17-8 8.290E-K09 63.530... 

Alkaline medium, however, is not always suitable since branched-chain alkyl halides are subject to elimination, and there are striking changes in orientation of substitution with unsymmetrically substituted imidazoles. Only low yields of l-(l-imidazolyl)-2-methyl-propane are obtained in the reaction of imidazole with l-iodo-2-methylpropane in sodium-liquid ammonia. 

Fig. 3. Synthesis of fluoxetine (31). 3-ChIoro-I-phenyl-I-propanol reacts with sodium iodide to afford the corresponding iodo derivative, followed by reaction with methylamine, to form 3-(methyl amin o)-1-phenyl-1-propan 0I. To the alkoxide of this product, generated using sodium hydride, 4-fluorobenzotrifluoride is added to yield after work-up the free base of the racemic fluoxetine (31), thence transformed to the hydrochloride (51)...

Hexalluoro-2-(2-iodo-5-methyIphenyl)propan-2-ol reacts with trifluoromethyl hypofluorite at -78 C in Freon 11 to give l-fluoro-5-methyl-3.3-bis(trifluoromethyl)-l,3-dihydro-l,2-benz-iodoxole (35) in high yield.57... 

S)-(+)-4-Methyl-3-heptanone SAMP-hydrazone 1-Pyrrolidinamine, N-(l-ethyl-2-methyl pentyl idene)-2-(methoxymethyl)-, [S-[R, R -(Z)]i- (10) (69943-24-4) Propyl iodide Propane, 1-iodo- (8,9) (107-08-4)... 

Argiiello, J.E., Penenory, A.B. and Rossi, R.A. (2000) Quantum yields of the initiation step and chain propagation turnovers in SRN1 reactions photostimulated reaction of l-iodo-2-methyl-2-phenyl propane with carbanions in DMSO. Journal of Organic Chemistry, 65, 7175-7182. 

Thus, addition of iodine monochloride and sodium azide to 1 -methylcyclobutene in acetonitrile gave rra i-l-azido-2-iodo-l-methylcyclobutane (1) in 70% yield. Lithium aluminum hydride reduction of this trans-0L,p- odiethyl ether at 20 °C gave, instead of the expected l-methyl-5-azabicyclo[2.1.0]pentane, the product of ring contraction, i.e. 1-aminoethylcyclo-propane (3). Formation of an intermediate 2-iodocyclobutylamine, which then underwent C4 -> C3 ring contraction, analogously to the 2-halocyclobutanols (Section 4.1.2.2.1) appeared likely to explain this result. 

Methyl-2,2-diphenylcyclopropanoylperoxide (17) is transformed into 1-chloro- and 1-iodo-l-methyl-2,2-diphenylcyclopropane (18, X = Cl, I) by heating in carbon tetrachloride or in a solution of iodine in carbon tetrachloride, respectively, albeit in poor yield.Decomposition of the (-)-(/ )-peroxide in tetrahydrofuran leads to 2-methy 1-1,1-diphenylcyclo-propane (18, X = H). In all cases complete racemization occurs. 

Cl 7H1 sFe20i, (Di-77 -cyclopentadienyldicarbonyliron)propane, 42B, 619 C17H1gl3N20Rh, Carbonyltri-iodo-(a-(N-methyl-a-methyliminobenzylam-ino)benzylidene-N,C)rhodium, 40B, 706 C17H2oMnNOg, Tetramethylammonium cis-acetylbenzoyltetracarbonyl-manganateU ), 42B, 620... 

The most known designer drugs are carphedone 4-chloro-2,5-dimethoxyphenethylamine (2C-C) i 5-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yM-methylpiperazine-l-carboxylate (zopiclone or Z-drug) 4-(N,N-dimethylamino sulfonyl)-7-fluoro-2,l,3-benzoxadiazole (DBD-F) dimethyltryptamine (DMTA) diphenydramine 4-ethyl-2,5-dimethoxyphenethylamine (2C-E) 4-ethylthio-2,5-dimethoxyphenethylamine (2C-T-2) 4-fluoroamphetamine (4-FMP) indan-2-amine 4-iodo-2,5-dimethoxyphenethylamine (2C-I) 1 -(4-iodo-2,5-dimethoxyphenyl)propan-2-amine (DOI) 4-isopropylthio-2,5-dimethyoxyphenethylamine (2C-T-4) meperidine 2-methylamino-l-(3,4-methylenedioxyphenyl)butan-l-one (Bk-MBDB) l-(3,4-methylenedioxybenzyl)piperazine (MDBP) 1 -(3,4-methylenedioxyphenyl)butan-2-amine (BDB) N-methyl-3,4-methylenedioxymethamphetamine (MMDA-2) N-methyl-1 -(3,4-methylenedioxyphenyl)butan-2-amine (HMDMA) N-methyl-l-(3,4-methylenedioxyphenyl)butan-3-amine (HMDMA) methylphenidate 4-methoxymethamphetamine (PMMA) l-(4-methoxyphenyl)piperazine (4-MPP) 2-(6-methyl-2-p-tolylimidazol[l,2-9]pyridine-3-yl)acetamide (zolpidem) normeperidine 4-phenylbutylamine (4-PBA) 3-phenyl-1-peopyTamine (3-PPA) and 2,4,6-trimethoxyamphetamine (TMA-6). 

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