Intravenous nutrition chromium

Direct determination of chromium in diet, in oral and intravenous nutritional support regimens, and in blood... 

Drs. Filer and Muller, at the University of Iowa, treated an 8 year old girl with total parenteral nutrition for three two-month periods because of a poorly mobile gastrointestinal tract. Each period of treatment was separated by 5 months of oral alimentation. Following the last period of total intravenous nutrition, the same solution was administered via jejunostomy for an additional month. At that time, plasma and hair measurements were made. Table 5 shows that zinc and copper concentrations were significantly low in both plasma and hair. The chromium and manganese concentrations, however, remained in the normal range. 

Plate 8 Total parental nutrition wherein up to three litres of a colloidal emulsion is administered intravenously per patient per day. Trace elements which are necessary for long-term TPjN include calcium, magnesium, iron, copper, zinc, cobalt, manganese, selenium, chromium, molybdenum, iodine, fluorine, phosphorus, chlorine, sodium, and potassium. Photograph provided by Kabi Pharmacia... 

The requirements for trace elements during nutritional support of ARF patients are not well established because trace element accumulation or losses during ARF have not been characterized. Additionally, many of the trace element alterations in ARF may in fact represent an acute phase reaction. " Zinc and chromium are excreted by the kidney and theoretically can accumulate due to reduced excretion and increased intake secondary to impurities in dialysate or intravenous fluids. In ARF patients undergoing CRRT, zinc intake via nutrition support has been shown to exceed patient losses. Selenium concentrations are... 

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