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Intestinal mucin molecule

Histochemical demonstration of most of the O-acetylated sialic acids is possible because substituents on the side chain of Neu hinder periodate oxidation of this part of the molecule to an extent dependent on the number and position of the O-acetyl groups already mentioned. Correspondingly, removal of these ester groups by alkaline treatment (0.5% KOH in 70% ethanol91) may increase the staining reaction of a sialic acid. For example, the presence of O-acylated sialic acids has been demonstrated in colonic, epithelial mucin of man and various mammals (summarized in Ref. 91), in healthy and diseased, human small-intestine,188-190 in bovine submandibular gland,182 in mouse and rat erythrocyte-membranes,191 and in human lymphocytes.192... [Pg.172]

The binding of calcium ions by the mucins of rat small intestines probably involves sialic acid and carboxy-groups, which co-operate to produce a contraction or folding of the molecule on binding of the cation. ... [Pg.319]

See other pages where Intestinal mucin molecule is mentioned: [Pg.13]    [Pg.13]    [Pg.276]    [Pg.1773]    [Pg.157]    [Pg.159]    [Pg.147]    [Pg.104]    [Pg.122]    [Pg.54]    [Pg.49]    [Pg.309]    [Pg.45]    [Pg.183]    [Pg.3]    [Pg.176]    [Pg.501]    [Pg.552]    [Pg.21]    [Pg.289]    [Pg.1355]   
See also in sourсe #XX -- [ Pg.13 ]



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