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Interleukin-1 receptor associated kinase IRAK

Jurrmann N, Brigelius-Flohe R, Bol GF. 2005. Curcumin blocks interleukin-1 (IL-1) signaling by inhibiting the recruitment of the IL-1 receptor-associated kinase IRAK in murine thymoma EL-4 cells. J Nutr 135 1859-1864. [Pg.390]

This receptor family mediates the effects of interleukin 1, a major proinflammatory cytokine, and interleukin 18, and includes TLR receptors of macrophages like TLR2 which recognize peptigoglycans of gram-positive bacteria. These receptors are coupled to the cytosohc serine/threonine kinase IRAK (interleukin receptor-associated kinase). Following signals include the activation of transcription factors like NFk,B, or others via MAP kinases. [Pg.98]

See other pages where Interleukin-1 receptor associated kinase IRAK is mentioned: [Pg.279]    [Pg.280]    [Pg.60]    [Pg.279]    [Pg.100]    [Pg.98]    [Pg.280]    [Pg.60]    [Pg.520]    [Pg.369]    [Pg.181]    [Pg.59]    [Pg.1239]    [Pg.548]    [Pg.1239]    [Pg.471]    [Pg.272]    [Pg.272]   
See also in sourсe #XX -- [ Pg.55 , Pg.57 ]



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