Interactions antibacterial-surfactant

As surfactants alter the permeability of mammalian cells it is not too surprising that, in spite of the differences between bacterial cell walls and mammalian cell membranes, some surfactants have the ability to increase the permeability of the bacterial cell wall or to act synergistically with antibacterial agents. There are several unique facets to discussion of this topic some surfactants have antibacterial properties and some antibacterial agents have surface-active properties. In considering the subject one has to be aware, as before, of surfactant antibacterial interactions, the influence of surfactant on the performance of the dosage form or formulation, and surfactant-cell wall interactions. 

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