Interaction of DNA with Divalent Metal Ions

It is considered that B-DNA type is the native form, its occurrence being favored by the increased polarity of the DNA due to the ionic status in DNA/M systems. 

If the polarity decreases, then under experimental conditions the C-DNA type appears. Then, due to an important 

This chapter deals with the interactions between DNA and divalent metal ions present in the organism ( biometals ) as bioconstituents or biochemical effectors (activa-tors/inhibitors) such as alkaline-earth metals (e.g., Ca, Mg) and the biologically active transition metals (e.g., Zn, Fe, Mn, 

In addition, the interactions of DNA with potentially toxic metals (Cd, Hg, Ni) or even with some biometals which, when present in excess, may be considered toxic (e.g., Gu, Go), are detailed. 

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Granot J, Kearns DR. Interactions of DNA with divalent metal ions. III. Extent of metal binding experiment and theory. Biopolymers 1982 21 219-232. 

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