Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Heme polymerizations inhibition

Kannan, R. Sahal, D. Chauhan, V. S. Heme-artemisinin adducts are crucial mediators of the ability of artemisisnin to inhibit heme polymerization. Chem. Biol, 2002, 9(3) 321-332. [Pg.256]

Different antimalarials selectively kill the parasite s different developmental forms. The mechanism of action is known for some of them pyrimethamine and dapsone inhibit dihydrofolate reductase (p. 273), as does chlorguanide (proguanil) via its active metabolite. The sulfonamide sulfadoxine inhibits synthesis of dihydrofolic acid (p. 272). Chlo-roquine and quinine accumulate within the acidic vacuoles of blood schizonts and inhibit polymerization of heme, the latter substance being toxic for the schizonts. [Pg.294]

See other pages where Heme polymerizations inhibition is mentioned: [Pg.243]    [Pg.348]    [Pg.243]    [Pg.348]    [Pg.1313]    [Pg.1313]    [Pg.336]    [Pg.343]    [Pg.347]    [Pg.237]    [Pg.511]    [Pg.260]    [Pg.333]    [Pg.362]    [Pg.294]    [Pg.238]    [Pg.3]    [Pg.148]    [Pg.135]    [Pg.459]    [Pg.461]    [Pg.113]    [Pg.149]    [Pg.154]   
See also in sourсe #XX -- [ Pg.348 ]



SEARCH



Polymerization inhibited

Polymerization inhibition

© 2024 chempedia.info