Influence surface energy model

Despite the fact that nonpolar hydration forces dominate whenever hydrophobic interactions [46] are important, the general availability of accurate models for the nonpolar component of the hydration-free energy is lacking. The structure and properties of proteins in water is highly influenced by hydrophobic interactions [47-50]. Hydrophobic interactions also play a key role in the mechanism of ligand binding to proteins [30,51-53], Empirical surface area models [54] for the nonpolar component of the solvation free energy are widely used [28,37,55-62]. Surface area models are useful as a first... 

The paper describes some of our studies of protein adsorption on solid surfaces. An emphasis is made on newly developed experimental techniques and on recent biological model experiments. We therefore discuss the use of a wettability gradient along a solid surface to Investigate, In a convenient way, the Influence of surface energy on the adsorption of protein molecules. The behavior of the complement system at solid surfaces Is also discussed, with special attention to surface Induced conformational changes of human complement factor 3. 

The argument for fixing the slope requires introducing an additional surface energy component [89] which is otherwise not present in the picture. There is a reason to believe that such a perturbation not only influences the contact slope, but also directly affects the barrier and modifies the membrane properties. That is why we think that the surface perturbation should be explicitly incorporated in the membrane model. 

A big amount of experimental studies of stability of many component systems Pt Me (where Me - transition metals Cr, Fe, Co, Ni, Ru) indicates about the formation of nanoclusters with core-shell structures [11-13], where mechanisms of the processes (including corrosive) with the formation of such structures are described. Firstly this is a surface segregation during the process of multicomponent nanocluster preparation [14], Due to such segregation nanocluster surface becomes enriched by one of the components, especially by platinum with the reduction of surface energy in segregated binary nanocluster [75]. In the process of corrosive influence (in model conditions or in tests of fuel cells) a prevailing dissolution of one component from basic metal Me and surface enrichment by platinum with the formation of a core-shell system. 

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