Optic neuropathy infiltrative

In infiltrative optic neuropathy, substances that are not normal to the optic nerve or nerve sheath accumulate within the optic nerve.This diffusion of material results in optic nerve dysfunction. Clinically, the loss of optic nerve function may result in loss of visual acuity, visual field defects, color vision defects, and RAPD. In some cases the optic disc is swollen because of infiltration of the prelam-inar or immediate retrolaminar region. An absence of disc swelling, with visual acuity loss, may occur secondary to infiltration of the retrolaminar portion of the nerve, which causes a retrobulbar optic neuropathy. 

Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by the deposition of noncaseating granulomas surroimded by lymphocytes. The infiltrative optic neuropathy in sarcoidosis may be the first and only ocular sign or may occur in conjunction with other ocular manifestations of sarcoidosis such as uveitis, candle-wax drippings (exudates around the retinal vessels), and choroidal granulomas. Optic disc edema... 

SLE is a multisystem, idiopathic, autoimmime disease characterized by infiltration of capillaries of collagen-vascular tissue by antibody-antigen complexes.The optic disc in SLE can be elevated, and there may be a painless reduction in visual acuity. SLE optic neittopathy may present as either a retrobulbar optic neittopathy or as an anterior ischemic optic neuropathy (AION). 

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