Indoramin Alcohol

ALCOHOL ALPHA-BLOCKERS T levels of both alcohol and indoramin occur with concurrent use Uncertain Warn patients about the risk of t sedation... 

In a fatality attributed to indoramin overdose, an antemortem plasma concentration of 6.4pg/ml was reported together with an alcohol concentration of 2250 pg/ml (R. Hunter, Br. med. J., 1982,285,1011). 

The plasma levels of both indoramin and alcohol may be raised by concurrent use. The combination of alcohol and indoramin has been reported to increase drowsiness, which may possibly increase the risks when driving or using machinery. Prazosin appears to enhance the hypotensive effects of alcohol. 

Information is limited but the interaction between indoramin and alcohol appears to be established. The clinical importance of the raised levels of both drugs is uncertain. However since indoramin sometimes causes drowsiness when it is first given, there is the possibility that alertness will be reduced, which could increase the risks of driving or handling machinery. Patients should be warned. Prazosin appears to enhance the hypotensive effect of alcohol, see also, Alcohol + Antihypertensives , p.48. 

For mention of the possibility of increased sedation with alcohol and clo-nidine or indoramin, see Clonidine and related drugs + CNS depressants , p.883 and Alcohol + Alpha blockers , p.42. 

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