Tabemaemontana indole alkaloids isolated from

B. Indole Alkaloids Isolated from Tabemaemontana Species. 9... 

In a paper published in 1991, Arambewela and Ranatunge describe the isolation of several indole alkaloids from Tabemaemontana divaricata (199). For one of them they presented structure 96 and called it 11-methoxy-Va-methyldihydropericyclivine, although this structure represents 11-methoxy-Na-methyldihydro-16-epipericyclivine (Fig. 6). Very few data were presented in support of the proposed structure 96 or its 16-epimer 97. In particular, the H NMR data S 2.43 (3H, s) and S 2.54 (3H, s) given for )N—CH3 and — COOCH3, respectively, do not support either of the epimerie structures. In the writers opinion, the claims concerning the presence of ll-methoxy-iVa-methyldihydro-16-epipericyclivine (96) or 11-methoxy-JVa-methyldihydropericyclivine (97) in T. divaricata must be considered premature. 

As one of the few indole alkaloids of the tacamane type, tacamonine (262) was isolated by Beek and co-workers from Tabemaemontana eglandulosa it possesses vasodilator and hypotensive activities. With the development of... 

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