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INDEX drug-induced

Ciclosporin is absorbed to a variable extent from the gastrointestinal tract and almost completely metabolized in both the liver and small intestine by CYP3A, which metabolizes a large number of drugs. Inducers, inhibitors, or substrates of CYP3A therefore have the potential to interact with ciclosporin. In addition, ciclosporin has wide pharmacokinetic variability and a narrow therapeutic index. Conversely, ciclosporin can inhibit the hepatic metabolism of other drugs that share the same CYP3A metabolic pathway. [Pg.759]

Multiple prescribing physicians Use of drugs with a low therapeutic index Use of drugs that are enzyme inhibitors or inducers Elderly... [Pg.840]

Monitoring A high index of suspicion for drug-related hepatic injury is critical if the occurrence of liver damage induced by naltrexone is to be detected at the earliest possible time. [Pg.389]

See other pages where INDEX drug-induced is mentioned: [Pg.54]    [Pg.634]    [Pg.646]    [Pg.492]    [Pg.259]    [Pg.368]    [Pg.315]    [Pg.345]    [Pg.247]    [Pg.61]    [Pg.701]    [Pg.2606]    [Pg.136]    [Pg.588]    [Pg.1154]    [Pg.1877]    [Pg.223]    [Pg.510]    [Pg.314]    [Pg.62]    [Pg.322]    [Pg.156]    [Pg.614]    [Pg.246]    [Pg.8]    [Pg.146]    [Pg.443]    [Pg.497]    [Pg.498]    [Pg.503]    [Pg.105]    [Pg.510]    [Pg.513]    [Pg.626]    [Pg.701]    [Pg.222]    [Pg.323]    [Pg.290]    [Pg.401]    [Pg.70]    [Pg.338]    [Pg.77]    [Pg.179]    [Pg.317]    [Pg.101]    [Pg.227]    [Pg.188]   
See also in sourсe #XX -- [ Pg.606 , Pg.1718 ]



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Drug-induced

Drugs indexes

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