2//-Indazoles, 2-substituted, lithiation

Indazole, 5,5-dimethyl-3-trifluoromethyl-4,5-dihydro-trichomonacidal activity, S, 291 Indazole, 2-ethoxycarbonyl-reactions, 5, 269 Indazole, 3-fluoro-synthesis, 5, 263 Indazole, 1-germyl-synthesis, 5, 236 Indazole, 1-glycosyl-synthesis, 5, 289 Indazole, 2-glycosyl-synthesis, 5, 289 Indazole, halo-reactions, S, 266 Indazole, 2-hydroxy-methylation, S, 269 Indazole, 3-hydroxy-reactions, S, 264 Indazole, 6-hydroxy-diazo coupling, S, 86 Indazole, hydroxyphenyl-synthesis, S, 288 Indazole, 3-iodo-synthesis, S, 241 Indazole, l-isopropyl-3-phenyl-reduction, S, 243 Indazole, 3-mercapto-1-substituted tautomerism, 5, 265 Indazole, m ethoxy-pharmaceutical activity, 5, 294 Indazole, 1-methyl-lithiation, S, 245 melting point, S, 207... 

Lithiation of 2-alkyl-2/f-indazoles proceeds straightforwardly and thus 3-substituted 2/f-indazoles can be obtained and comparable lithiations of 2-trimethylsilyl-indazoles, followed by removal of the silicon substituent, produce 3-substituted indazoles. 

---