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In-vivo Data of GnRH Binding Spiegelmers

Immunogenicity is one major concern with macromolecular drugs. For this reason NOX 1255 and 1257 were analyzed for their immunogenic potential. Both [Pg.258]

Activity in rat model, LH level Significant effect between 1 Decrease of LH level to [Pg.259]

The author would like to thank Britta Wlotzka and Robert McLeod for helpful discussions and critical reading of the manuscript. [Pg.259]

Encyclopedia of Analytical Chemistry, R. Meyers, ed., John Wiley and Sons, Chichester, 2000, pp. 4848-4871. [Pg.261]

Pasteur, Compt. Rend. Hebt. Acad. Sci. Paris 1848, 26, 534-538. [Pg.261]


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Binding data

GnRH

In vivo data

Spiegelmers

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