Implications for Odorant Design

The pharmaceutical industry builds pharmacophores. These are models defining the requisites for a given activity. They include such features as overall shape and electron distribution, hydrogen-bonding centres, hydro-phobic bulk and excluded space (i.e. areas of space around the target 

Congress of Flavours, Fragrances and Essential Oils, K.H.C. Baser (ed), AREP Publishers, Istanbul, 1995, vol. 3, p. 1. 

Deutsch and R. Apfelbach, AChemS, 25th Annual Meeting, Florida, 

Hummel, C. Hummel, E. Pauli and G. Kobal, Chem. Senses, 1992, 

Laffort, in Odours and Deodorisation in the Environment, G. Martin and P. Laffort (eds), VCH Publishers, New York, 1994, 143. 

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