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Immunological reaction with peptides

Modification of both tryptophanyl residues in a two-disulphide peptide of lysozyme by reaction with 2,3-dioxo-5-indolinesulphonic acid gave a derivative possessing a similar conformation to that of the unmodified peptide. Immunological and o.r.d. and c.d. spectroscopic studies of the modified peptide yielded information on the structure of the antigenic site of the enzyme. [Pg.480]

Sorg C, Riide E, Westphal O (1970) Immunological properties of amylose, dextran and polyvinyl alcohol conjugate with polytyrosyl peptides. Eur J Biochem 17 85-90 Spaeth GL, Spaeth EB, Spaeth PG, Lucier AC (1967) Anaphylactic reaction to mannitol. Arch Ophthalmol 78 583-584... [Pg.626]

Immunologic A patient with a hemopoietic stem cell transplant and a history of an immediate hypersenstivity reaction to mica-fungin was considered for a trial of caspofungin, but a caspofungin intradermal skin test was positive, suggesting cross-reactivity [86" ]. Thus, the cyclic peptide nucleus chemical structure shared by echinocandins may be the site of IgE recognition, and it would be prudent to avoid challenging patients with history of immediate hypersensitivity to one echinocandin with another. [Pg.557]

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See also in sourсe #XX -- [ Pg.235 ]



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